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中央加密系统 1

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多齿加密-解密算法 1

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数字签名 1

生成锁 1

网络电子身份 1

网络编码；无证书多重签名；线性组合；同态哈希函数 1

群签名；格密码；验证者本地撤销；后向无关联性；小整数解难题 1

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防二重认证签名；变色龙哈希函数；数字签名；可证明安全；权威信任层次 1

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Design of bio-oil additives via molecular signature descriptors using a multi-stage computer-aided molecular

《化学科学与工程前沿（英文）》 2022年第16卷第2期页码 168-182 doi: 10.1007/s11705-021-2056-8

摘要： Direct application of bio-oil from fast pyrolysis as a fuel has remained a challenge due to its undesirable attributes such as low heating value, high viscosity, high corrosiveness and storage instability. Solvent addition is a simple method for circumventing these disadvantages to allow further processing and storage. In this work, computer-aided molecular design tools were developed to design optimal solvents to upgrade bio-oil whilst having low environmental impact. Firstly, target solvent requirements were translated into measurable physical properties. As different property prediction models consist different levels of structural information, molecular signature descriptor was used as a common platform to formulate the design problem. Because of the differences in the required structural information of different property prediction models, signatures of different heights were needed in formulating the design problem. Due to the combinatorial nature of higher-order signatures, the complexity of a computer-aided molecular design problem increases with the height of signatures. Thus, a multi-stage framework was developed by developing consistency rules that restrict the number of higher-order signatures. Finally, phase stability analysis was conducted to evaluate the stability of the solvent-oil blend. As a result, optimal solvents that improve the solvent-oil blend properties while displaying low environmental impact were identified.

关键词： computer-aided molecular design bio-oil additives molecular signature descriptor

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NTRU格上基于身份签名的高效方案

Jia XIE,Yu-pu HU,Jun-tao GAO,Wen GAO

《信息与电子工程前沿（英文）》 2016年第17卷第2期页码 135-142 doi: 10.1631/FITEE.1500197

摘要：

Identity-based signature has become an important technique for lightweight authentication as soon as it was proposed in 1984. Thereafter, identity-based signature schemes based on the integer factorization problem and discrete logarithm problem were proposed one after another. Nevertheless, the rapid development of quantum computers makes them insecure. Recently,many efforts have been made to construct identity-based signatures over lattice assumptions against attacks in the quantum era.However, their efficiency is not very satisfactory. In this study, an efficient identity-based signature scheme is presented over the number theory research unit (NTRU) lattice assumption. The new scheme is more efficient than other lattice- and identity-based signature schemes. The new scheme proves to be unforgeable against the adaptively chosen message attack in the random oracle model under the hardness of the γ-shortest vector problem on the NTRU lattice.

关键词： Identity Signature Lattice Number theory research unit (NTRU)

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面向网络编码的无证书多重签名方法 Research Article

俞惠芳,亓哲伟

《信息与电子工程前沿（英文）》 2022年第23卷第9期页码 1369-1377 doi: 10.1631/FITEE.2200271

摘要：比起具有转储功能的传统路由技术，网络编码能节省网络资源且速度快。但在实际应用场景中，网络编码容易受到污染攻击和伪造攻击。本文针对这些问题提出面向网络编码的无证书广播多重签名（NC-CLBMS）方法，每个源节点用户生成对消息向量的多重签名，中间节点将接收到的数据线性组合。NC-CLBMS是一种多源的多重签名方法，具有抗污染和防止伪造攻击的功能；此外，它还具有固定的签名长度和较高的计算效率。本文设计的NC-CLBMS在无人机通信网络、5G无线网络、无线传感器网络、移动无线网络和车联网等方面具有广泛应用前景。

关键词：网络编码；无证书多重签名；线性组合；同态哈希函数

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Machine learning modeling identifies hypertrophic cardiomyopathy subtypes with genetic signature

《医学前沿（英文）》 2023年第17卷第4期页码 768-780 doi: 10.1007/s11684-023-0982-1

摘要： Previous studies have revealed that patients with hypertrophic cardiomyopathy (HCM) exhibit differences in symptom severity and prognosis, indicating potential HCM subtypes among these patients. Here, 793 patients with HCM were recruited at an average follow-up of 32.78 ± 27.58 months to identify potential HCM subtypes by performing consensus clustering on the basis of their echocardiography features. Furthermore, we proposed a systematic method for illustrating the relationship between the phenotype and genotype of each HCM subtype by using machine learning modeling and interactome network detection techniques based on whole-exome sequencing data. Another independent cohort that consisted of 414 patients with HCM was recruited to replicate the findings. Consequently, two subtypes characterized by different clinical outcomes were identified in HCM. Patients with subtype 2 presented asymmetric septal hypertrophy associated with a stable course, while those with subtype 1 displayed left ventricular systolic dysfunction and aggressive progression. Machine learning modeling based on personal whole-exome data identified 46 genes with mutation burden that could accurately predict subtype propensities. Furthermore, the patients in another cohort predicted as subtype 1 by the 46-gene model presented increased left ventricular end-diastolic diameter and reduced left ventricular ejection fraction. By employing echocardiography and genetic screening for the 46 genes, HCM can be classified into two subtypes with distinct clinical outcomes.

关键词： machine learning methods hypertrophic cardiomyopathy genetic risk

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格上高效的身份基签名

陈江山1,2,胡予濮1,梁红梅2,高雯3

《信息与电子工程前沿（英文）》 2021年第22卷第2期页码 141-286 doi: 10.1631/FITEE.1900318

摘要：随着电子信息技术的飞速发展，数字签名已成为人们生活中不可或缺的一部分。由于证书管理的局限性，传统的公钥证书密码系统无法满足现有需求。基于身份的密码系统避免了证书管理问题。量子计算机的发展给传统密码学带来严峻挑战。后量子密码学研究势在必行。目前，几乎所有后量子基于身份的签名方案都是利用高斯采样技术或陷门技术构建的。但是，这两种技术对计算效率有很大影响。为克服该问题，采用Lyubashevsky签名方案构造了格上基于身份的签名方案。基于格上的最短向量问题，该方案既不使用高斯采样技术也不使用陷门技术。在随机谕言机模型中，可以证明该方案对适应性选择的消息和身份攻击是不可伪造的。其安全性级别是强不可伪造的，比其他方案存在性不可伪造的安全性更高。与其他有效方案相比，所提方案在计算复杂度和安全性方面具有优势。

关键词：身份基签名；格；强不可伪造性；随机谕言机模型

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Carcinogens that induce the A:T>T:A nucleotide substitutions in the genome

null

《医学前沿（英文）》 2018年第12卷第2期页码 236-238 doi: 10.1007/s11684-017-0611-y

摘要：

Recently, Ng . reported that the A:T>T:A substitutions, proposed to be a signature of aristolochic acid (AA) exposure, were detected in 76/98 (78%) of patients with hepatocellular carcinoma (HCC) from the Taiwan Province of China, and 47% to 1.7% of HCCs from the Chinese mainland and other countries harbored the nucleotide changes. However, other carcinogens, e.g., tobacco carcinogens 4-aminobiphenyl and 1,3-butadiene, air toxic vinyl chloride and its reactive metabolites chloroethylene oxide, melphalan and chlorambucil, also cause this signature in the genome. Since tobacco smoke is a worldwide public health threat and vinyl chloride distributes globally and is an air pollutant in Taiwan Province, the estimation of the patients’ exposure history is the key to determine the “culprit” of the A:T>T:A mutations. Apparently, without estimation of the patients’ exposure history, the conclusion of Ng is unpersuasive and misleading.

关键词： genomic signature carcinogen aristolochic acid tobacco smoke vinyl chloride hepatocellular carcinoma

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量子密码协议研究现状与未来发展

张雪,高飞,秦素娟,张平

《中国工程科学》 2022年第24卷第4期页码 145-155 doi: 10.15302/J-SSCAE-2022.04.015

摘要： High-efficiency continuous-variable quantum digital signature protocol for signing multi-bit messagesQuantum digital signature for the access control of sensitive data in the big data era [J].Securing blockchain transactions using quantum teleportation and quantum digital signature [J].

关键词：量子密码协议量子密钥分配量子数字签名量子保密查询

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全球主要国家和地区网络电子身份管理发展与应用

胡传平,陈兵,方滨兴、邹翔

《中国工程科学》 2016年第18卷第6期页码 99-103 doi: 10.15302/J-SSCAE-2016.06.020

摘要：

本文对世界主要国家和地区网络电子身份管理的最新进展、典型应用以及我国网络电子身份管理与应用等情况进行了全面的分析与梳理，并结合网络身份管理技术的发展趋势，提出“十三五”期间我国网络电子身份管理的发展思路和建设性意见，旨在加强网络空间身份管理，构建网络空间身份管理体系，同时有助于规范网民行为、防范打击网络犯罪、构建网络强国、维护国家安全和网络空间主权、保护网络用户的个人隐私，以期为“十三五”期间我国网络身份管理发展提供借鉴和参考。

关键词：网络电子身份身份管理数字签名

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生成锁P<G,X,X'>和它的中央加密系统

史开泉,陈泽雄

《中国工程科学》 2000年第2卷第2期页码 41-46

摘要：

利用数据生成技术，提出生成锁P <G ,X, X´>的概念和由P <G ,X, X´>构成的中央加密系统。这些系统是：生成锁P <G ,X, X´>与单齿中央加密系统，生成锁P <G ,X, X´>与多齿中央加密系统。给出单齿加密-解密算法，多齿加密-解密算法，多齿静态加密-解密算法，多齿动态加密-解密算法，中央加密系统的结构特性。研究指出：任意两个秘密通讯的双方A和B，它们各自选择无规则分布的正整数集合X_A={x₁，x₂，…，x_n}，X_B={x₁，x₂，…，x_m}，m,n≥4，X_A≠X_B，利用P <G ,X, X´>完成双方之间的秘密通讯。研究结果表明，所提出的方法具有良好的应用性，安全性。

关键词：生成锁中央加密系统多齿加密-解密算法 P X X'>存在定理数位签章唯一性定理

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格上后向无关联性安全的验证者本地撤销群签名 Research Articles

张彦华1,刘西蒙2,胡予濮3,甘勇4,贾惠文5

《信息与电子工程前沿（英文）》 2022年第23卷第6期页码 876-892 doi: 10.1631/FITEE.2000507

摘要：

群成员可撤销的群签名中，验证者本地撤销机制似乎是一种更为灵活的选择，因为在签名验证过程中，仅需验证者获取最新的撤销信息，而不涉及签名者。与经典的数论型构造相对应，Langlois等人给出了后量子安全的首个格上验证者本地撤销群签名。然而，截至目前，所有格上验证者本地撤销群签名方案暂不满足后向无关联性，该特性可保障群成员被撤销前其对消息签名的匿名性和无关联性。本文给出了首个格上后向无关联性安全的验证者本地撤销群签名方案，从而解决了这一公开问题。新方案为群公钥和群成员签名密钥节省了O(log N)的比特大小，并且没有任何公钥加密。特别地，新方案在随机谕言机模型下是可证明安全的，其困难性可归约至两个经典格上难题假设，即小整数解难题和差错学习难题。

关键词：群签名；格密码；验证者本地撤销；后向无关联性；小整数解难题

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再议防二重认证签名：新定义和基于变色龙哈希的构造 None

Fei LI, Wei GAO, Gui-lin WANG, Ke-fei CHEN, Chun-ming TANG

《信息与电子工程前沿（英文）》 2019年第20卷第2期页码 176-186 doi: 10.1631/FITEE.1700005

摘要：防二重认证签名（DAPS）是在ESORICS 2014会议上提出的一种新型电子签名。防二重认证性质指同一主题上两个不同消息的签名可以用来摧毁整个签名体系。其提出者已指出防二重认证签名的几个潜在应用场景，比如，在数字证书领域，可以提供针对证书颁发机构（CA）的自我约束体制，使其不敢违规提供假冒证书。本文主要考虑防二重认证签名的基础性质。提出一种适度弱化条件的新定义，同时为刻画防二重认证性质而保持足够性质强度。提出带密钥泄露的可逆变色龙哈希函数的新密码原型。提出防二重认证签名方案的通用构造，同时基于带密钥泄露的可逆变色龙哈希函数性质给出安全性证明。在此通用型防二重认证签名方案框架下，分别基于整数分解、不对称密码算法（RSA）和狄菲-赫尔曼计算（CDH）假设构造了3个具体的防二重认证签名方案。这些方案比现有的防二重认证签名方案效率更高。相比现有方案，分别基于RSA和CDH的两个新方案不再依赖可信系统建立模型。

关键词：防二重认证签名；变色龙哈希函数；数字签名；可证明安全；权威信任层次

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标题作者时间类型操作

Design of bio-oil additives via molecular signature descriptors using a multi-stage computer-aided molecular

期刊论文

NTRU格上基于身份签名的高效方案

Jia XIE,Yu-pu HU,Jun-tao GAO,Wen GAO

期刊论文

面向网络编码的无证书多重签名方法

俞惠芳,亓哲伟

期刊论文

Machine learning modeling identifies hypertrophic cardiomyopathy subtypes with genetic signature